Science and evidence
Evidence model
The refusals are part of the product, not gaps in it. When Livemore Bio cannot answer from admitted evidence, it names the missing measurement instead of producing a plausible-looking number.
Result fields
| Field | What it tells you |
|---|---|
evidence_state |
What kind of result it is, for example MODELED_ONLY, MODELED_MECHANISTIC or MODELED_STEADY_STATE |
qualification_state |
Whether it has been qualified against independent measurements. Nothing is qualified today: results are NOT_QUALIFIED, and research comparisons wait at REVIEW_REQUIRED |
applicability · interpretation_limits |
Where the protocol defines them: the physiology and context the model covers, and what it does not cover |
controls |
Checks that run on every execution: zero-dose equals untreated, mass balance, conservation |
claims_allowed · claims_prohibited |
Where the protocol defines them: which statements the result can and cannot support |
calibration_authorized |
Always false until an independent evidence review authorizes calibration. No model calibrates itself |
| provenance | Input and source SHA-256 digests, the pinned model commit, the solver and its version, and the citation behind each parameter |
Validation levels
Every claim states its validation level.
- A visual demonstration is not scientific validation.
- A simulation is not clinical validation.
- A wet-lab signal is not human efficacy.
Telemetry from the LIFE Patch updates observed state only and never silently recalibrates a model. Calibration stays unauthorized until an independent evidence review allows it: no model calibrates itself.
Not built yet
- The physical LIFE Patch. The B0 EVT design target has known electrical release blockers.
- The Cendos wet lab.
- Person-calibrated or context-validated models.
- Production PHI handling.
How to evaluate Livemore Bio
- Try to make it lie. Ask for a dose nobody measured, a compound with no pharmacokinetic source, or a twin with no admitted model. Each should refuse with a reason code and name the missing measurement.
- Read the
controlsblock. A zero-dose arm must reproduce the untreated arm exactly, and conservation identities must hold. These run on every execution, not on request. - Read
evidence_stateandqualification_state. Every result is a modeled state, and nothing is qualified. Nothing here claims to be validated. - Check the provenance. Every number carries its pinned sources, solver and citations.
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