Whole-human coverage

Livemore Bio registers every body system from the start and tracks each system's scientific maturity separately. Including a system in the architecture never counts as evidence that it works. This summary comes from livemore manifest on release stable 6588707.

Body systems

Body system	Functional claim	Executable models
Endocrine	`MODELED_CONTEXT_ONLY`	Bergman glucose–insulin
Cardiovascular	`MODELED_CONTEXT_ONLY`	O'Hara–Rudy CiPA 2017, heart-rate model
Digestive, hepatobiliary and exocrine pancreatic	`UNAVAILABLE`	partial: oral one-compartment hepatic PK
Urinary and renal regulatory	`UNAVAILABLE`	partial: renal covariate for metformin clearance
Integumentary, skeletal and articular, muscular and fascial, nervous, special sensory, blood and hematopoietic, lymphatic and immune, respiratory, reproductive, microbiome, and interstitial, extracellular-matrix and body-cavity interfaces	`UNAVAILABLE`	registered and reference-backed, with no engine yet

The maturity ladder

Each system is scored separately on each rung, and a rung is earned only with its own evidence.

Rung	Systems
Registered	15 of 15
Reference-backed	15 of 15
Modeled	2 of 15
Coupled	2 of 15
Person-calibrated	0 of 15
Context-validated	0 of 15
Independently replicated	0 of 15
Device-connected	0 of 15

The coupling between the two modeled systems, endocrine and cardiovascular, is a labelled hypothesis: its magnitude has no admitted source yet.

Reading the manifest yourself

livemore manifest

prints the whole-human capability and maturity as JSON. From Python:

from livemorebio import whole_human_manifest

manifest = whole_human_manifest()
manifest["coverage"]["registered_systems"], manifest["coverage"]["modeled_systems"]   # (15, 2)

The REST equivalent is GET http://127.0.0.1:8850/api/system-manifest.